Post

Visualizzazione dei post da ottobre, 2018

Osteoporosi: un lattobacillo può curarla

Immagine
Journal of Internal Medicine  Volume 284, Issue 3 Original Article Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: a randomized, placebo‐controlled, double‐blind, clinical trial A. G. Nilsson, D. Sundh, F. Bäckhed, M. Lorentzon First published: 21 June 2018 https://doi.org/10.1111/joim.1280Re Abstract Background The importance of the gut microbiome for bone metabolism in mice has recently been demonstrated, but no studies are available in humans. Lactobacillus reuteri ATCCPTA 6475 (L. reuteri 6475) has been reported to increase bone mineral density (BMD) in mice but its effect on the human skeleton is unknown. The objective of this trial was to investigate if L. reuteri6475 affects bone loss in older women with low BMD. Methods In this double‐blind, placebo‐controlled study, women from the population who were 75 to 80 years old and had low BMD were randomized to orally receive 1010 colony‐forming units of L. reuteri647